Sentimental Graffiti 2 takes place after the first game, with Kouhei Shiina, a second-year university student, as its protagonist. The story follows Kouhei's journey as he searches for models for his photography exhibition at college and meets twelve heroines, who were present in the original game. However, the original protagonist has passed away, and this new character must form relationships with these ladies.
The gameplay involves exploring both 1st-person and 3rd-person isometric perspectives. In the 1st-person view, you communicate with characters and examine close-up locations. The isometric perspective is used to navigate through a city featuring many locations, each with its own unique graphics based on the time of day. The map includes 29 locations, which can be further explored from within some of them. Your actions cost time, and the clock progresses as you move around or interact with the environment.