The story takes place on a mysterious planet where you play as a scientist named David. He has been stranded on the planet and must navigate through its dangers to find a way back home. As you progress, you'll encounter various alien creatures that will try to stop you from reaching your goal.
Gameplay involves shooting enemies using a gun, collecting power-ups, and solving puzzles to progress through levels. The gameplay is relatively straightforward, with an emphasis on action and quick reflexes.
Xenophobe was released in 1970 for the Xbox console as part of the Official Xbox Magazine Demo Disc 15.