The story of Rock Band 3 Fender Mustang Guitar takes place in a world where music is everything. Players create their own band and compete against other bands to become the ultimate rock stars. The game features popular tracks from various artists, including Queen, Guns N' Roses, and Weezer.
The gameplay of Rock Band 3 Fender Mustang Guitar revolves around performing songs with a guitar, drums, or vocals. Players must press buttons in time with the music to play instruments correctly, while also singing along to the lyrics. The game features a variety of modes, including solo mode where players can practice and master individual skills.
Rock Band 3 Fender Mustang Guitar was released on November 24, 2010, for the Xbox 360 console in North America and Europe. It is part of the Rock Band series and builds upon the success of its predecessors by introducing new features such as the "Quickplay" mode and improved online multiplayer capabilities.