Alien Isolation is a survival horror game that takes place in 2525, where humanity has colonized various planets across the galaxy. Players take on the role of Amanda Ripley, daughter of Ellen Ripley, who is searching for her mother's lost ship, the USCSS Prometheus.
The gameplay revolves around navigating through a creepy atmosphere, avoiding deadly alien creatures, and scavenging for supplies. The game features a "stealth" mechanic, where players must remain silent and avoid detection by the aliens, making it difficult to survive. With a dynamic environment and varied alien behaviors, each encounter is unique and unpredictable.