Scooby Doo Unmasked follows the gang as they travel across the United States, solving mysteries and uncovering supernatural secrets. The team is led by Fred, Daphne, Velma, Shaggy, and Scooby, who use their unique skills to overcome obstacles and stay one step ahead of their enemies.
Players take on the role of Shaggy and Scooby, navigating through levels and fighting monsters. The gameplay involves platforming, combat, and puzzle-solving, all set to a funky 80s-inspired soundtrack. The team's dynamic is also reflected in the game, with each character having their own strengths and weaknesses.