Daphne Blake is a key member of Mystery Inc. who appears as a playable character in the action-adventure games Scooby-Doo! First Frights (2009) and Scooby-Doo! and the Spooky Swamp (2010). In these titles, she possesses unique athletic abilities, such as climbing pipes and using a pole to fight enemies and solve puzzles.
Her transition into interactive media expanded her role from a traditional damsel in distress to an active, combat-oriented protagonist. In
Scooby-Doo! First Frights (2009), players can unlock various alternative costumes for her, including a gothic outfit and a cheerleader uniform, which alter her aesthetic during cooperative gameplay. This design philosophy carried over into
Scooby-Doo! and the Spooky Swamp (2010), where her cooperative mechanics with other franchise members were further refined, allowing for seamless drop-in, drop-out multiplayer dynamics.
Outside of official Warner Bros. Interactive Entertainment releases, the character's likeness has appeared in community-created modifications for seminal titles, most notably within custom total conversion wads for
Doom (1995). These fan projects adapt her cartoon aesthetic into the first-person shooter engine, demonstrating her cross-genre appeal. Across these diverse digital appearances, her voice is frequently provided by actress Grey DeLisle, maintaining audio consistency with the animated television series and films of the era.