Nicalis Inc. is known for publishing and porting prominent indie games and classic revivals to modern platforms. The company published titles such as 1001 Spikes, VVVVVV, Tiny Barbarian DX, and The End is Nigh, alongside physical editions of the shoot 'em up Ikaruga. They also published the Nintendo Switch physical release of Wonder Boy: The Dragon's Trap, tying them to the historic Wonder Boy franchise.
Collaborations with independent creators defined the publisher's mid-2010s catalog. For the 2014 release of
1001 Spikes, the company worked alongside 8bits Fanatics to expand the challenging platformer to major home consoles and handhelds. The 2015 adaptation of
VVVVVV brought Terry Cavanagh’s gravity-flipping design to portable systems, optimizing the title's retro aesthetic for new audiences.
The publisher established a distinct industry niche by producing premium physical packages that appealed to collectors. This strategy was central to the 2017 release of
Wonder Boy: The Dragon's Trap on the Nintendo Switch, where packaged copies included full-color instruction manuals and soundtrack samplers, honoring the heritage of the
Wonder Boy series. Similar physical treatments were applied to the 2017 releases of
Tiny Barbarian DX and
The End is Nigh. In 2018, the company partnered with developer Treasure to bring the legendary shoot 'em up
Ikaruga to modern consoles. This partnership culminated in the
Ikaruga [Ginkei Print] edition, a specialized physical release featuring exclusive cover art and collectible merchandise, cementing the publisher's role in preserving arcade history.