The game follows Wile E. Coyote as he tries to catch the Road Runner, while navigating through various desert landscapes and obstacles. The Road Runner's constant escape attempts are foiled by the coyote's own ACME brand contraptions, leading to humorous and chaotic consequences.
Players control Wile E. Coyote as he explores different levels, collecting items and power-ups while avoiding the Road Runner. The gameplay involves platforming, puzzle-solving, and combat with enemies, all set to a fun and catchy soundtrack.