Mr. Do! is a challenging action-adventure game where you control Mr. Do as he attempts to collect all of the cherries on the screen. However, there are numerous enemies trying to stop him! Mr. Do can defend himself in two ways: by pushing apples on top of the enemies and crushing them, or using his power ball to destroy an enemy. Unfortunately, Mr. Do only has one power ball, so he'll need to wait for it to return to him before using it again. Occasionally, an alpha monster will appear on the screen bearing a letter in the word EXTRA. If you use the power ball to destroy an alpha monster, you earn that letter; when you've earned all of the letters, you receive an extra life. When Mr. Do successfully collects all of the cherries, he moves on to the next level.
The mobile version of Mr. Do! includes both the original arcade version and an enhanced mode with new levels, power-ups, and graphics.