The combat gameplay has remained largely unchanged, but with added events and mini-games that require players to interact with their surroundings in different ways. For example, players need to twist the Wii remote to tune into radio broadcasts, while others require raising the Nunchuk to pump a shotgun. The game also introduces new weapons such as bazookas and mortars.
The game supports up to 32 players in simultaneous multiplayer matches, with various game modes like Death Match, Team Death Match, and Infiltration. Multiplayer maps are adaptations of the single-player levels.