Everett's main concern is to flee from zombies and travel to Macon where his parents and brother live. He soon meets Clementine, a small girl whose house has been overrun by zombies, and takes her along. The episode ends with the team deciding to stay at a Motor Inn as their home and build up a defence.
The game has conversation options that can alter the outcome of events. A timer runs down during conversations, and if none is chosen, there is one selected by default. The setting can be altered mid-game, with crucial choices remembered for later scenes and episodes.