Gameplay in NFL GameDay 2001 is fast-paced and immersive, with a focus on authentic football experience. You'll control your team's every move, from running plays to throwing passes, all while managing your players' skills and abilities. The game features improved graphics, commentary by Dick Enberg and Phil Simms, and innovative passing mechanics like total-control passing and running. The play editor allows for easy creation of new patterns, while the general manager mode provides valuable insights into team needs, making it easier to build a winning roster.