The story of Shiritsu Justice Gakuen: Nekketsu Seisyun Nikki 2 follows that of a young student who attends a prestigious school, where students are divided into houses. The main character is part of the lower-ranked house, which becomes the underdog in their rivalry with the more affluent upper-ranked house. As the story progresses, the main character's goal shifts from simply surviving to taking revenge against their tormentors.
The gameplay in Shiritsu Justice Gakuen: Nekketsu Seisyun Nikki 2 is a fighting game where players can choose from various characters with unique abilities. The game features an "overdrive" system, which allows characters to perform more powerful attacks when their health is low. Players must strategically use their character's abilities and items to defeat their opponents.