When New York City is attacked by aliens, the greatest heroes (and villains) in the Marvel Universe confront them. Marvel Nemesis: Rise of the Imperfects has two playing modes, a single-player story mode, where players brawl their way through a Mark Millar scripted tale, and a single- or two-player versus mode pitting heroes and villains against each other in a sandbox arena.
Famous Marvel characters have been reimagined by artist Jae Lee and new characters have been created for this game series. The Gamecube , PS2, and Xbox versions support online play and all versions have unlockable arenas, characters, and extras.