The gameplay in Nickelodeon Teenage Mutant Ninja Turtles is fast-paced and action-packed, with players controlling each of the four brothers as they battle through hordes of Foot Clan soldiers. The game features a variety of moves and special abilities for each turtle, allowing players to switch between them on the fly. With its mix of martial arts combat and ninja skills, Nickelodeon Teenage Mutant Ninja Turtles is a classic beat-em-up experience.