Painkiller: Hell & Damnation is an enhanced remake based on the original Painkiller and the expansion Painkiller: Battle Out of Hell . Of the 34 levels originally available in those games, 14 are featured in this title reorganized in four chapters. Each chapter has a boss and they were reconstructed with changes to the level design and the enemies. There is also a global graphical overhaul courtesy of converting the game from the original Pain engine to UnrealEngine3.
The gameplay features fast-paced action, with a focus on combat and exploration. The new weapon, Soulcatcher, allows for efficient soul collection. The game includes cooperative multiplayer modes, including local and online play, as well as a survival mode where up to eight players can fight together against hordes of enemies.
The game starts with a new intro cinematic that changes the setup of Daniel Garner's trip to purgatory. New tracks by Ojo Rojo complement the original music. The game also features uncut content, including the original PvP multiplayer modes.