To control Mike Tyson's alter ego, players must master various punching techniques to outbox opponents. As Tyson fights his way through a series of opponents, he gains skills such as 'hooks' and 'uppercuts', each increasing his chances of landing the winning punch.
Gameplay revolves around one-on-one boxing matches where players can choose from a variety of opponents and training modes to improve their skills. Players control Tyson's character using special moves and timing, trying to knock out opponents before they do the same to them.