Fuse is a game of teamwork, allowing players to switch between characters during battle using the LEAP system. This feature enables players to utilize each agent's specific skill set, working together to overcome challenges. The game supports two-player split-screen co-op and up to four players in co-op online. As players progress through the game, they earn experience to unlock abilities and upgrade weapons. Each agent also has a unique skill tree that allows for further customization of their character.