Aya Brea is back in a new game, Parasite Eve II , with fewer RPG elements than the first game. The gameplay plays more like Resident Evil. Battles are now entirely action-oriented, and a new range of weapons is available. Defeating enemies rewards money as well as points used to revive and power-up Aya's suppressed Parasite powers.
Aya left her job as a cop after surviving the events of Parasite Eve and joined MIST to hunt down the remnant mutants spawned by Eve's awakening. In 2000, a new breed of Neo Mitochondrion takes over the Akropolis Tower in downtown LA. Aya is called in and uncovers a secret organization that threatens all humanity.
The gameplay features action-oriented battles with a focus on defeating enemies to collect rewards. Weapons and armor have fixed stats, but attachments can be swapped out to modify their properties.