The game is also an installment in the Darkstalkers franchise, presenting a collection of all eighteen characters and four different play modes available in the series. Like in previous games, the playable characters are monsters and supernatural creatures, such as vampires, werewolves, demons, zombies and mummies, instead of regular boxers or martial artists.
The gameplay is standard fighting game fare, with players able to choose from eighteen different characters and engage in one-on-one battles. The game features various stages, special moves, and combos, all typical of a 2D fighting game.