WWF WrestleMania 2000

Players can select from 16 wrestlers for play in five single-player modes. The main story mode is Championship mode, where the player's wrestler competes for the WWF title, with TV-style cutscenes between matches. Vs. mode allows for single matches between two wrestlers, while Tag Team mode features single two-versus-two matches. Survivor Series mode requires assembling two teams of three wrestlers each, and Fights are one-on-one until one side's roster is empty. Gauntlet mode features a series of consecutive fights against all other wrestlers, and a training mode where the opponent doesn't fight back.

A two-player mode is supported via the link cable: two players can match up in single matches with normal and cage matches being available.

During a fight, the ring is seen from the side and scrolls in all four directions. The Game Boy's two buttons are used for context-sensitive moves depending on where the opponent is located. When in a grapple, buttons plus control pad directions allow for more variety in moves. Each wrestler also comes with his own finishing move, activated through pushing Select while in a grapple. These moves can't be activated at any time: each wrestler has their own bio-rhythm and the finisher can only be unleashed when their rhythm is at its peak.