The game features three difficulty levels, differentiating them by changing the way the interface works. The easiest level displays names of the notes as well as marking the correspondent areas on the distaff; Standard level features the distaff with the marks at the bottom of the screen, but no written notes; whereas Expert does not display the marks at all, requiring the player to memorize and play the drafts by ear.
The CD DOS version of Loom has enhanced 256-color graphics, audio tracks, and full voice acting. However, it also removes a few close-up scenes and conversations. The FM Towns version preserves these scenes and includes similar graphical and musical enhancements, but has no voice acting.