Innocent Life: A Futuristic Harvest Moon is a new generation of the Harvest Moon series. Unlike all previous games, the player can only choose their main character's name when starting the game. The game takes place in 2022 on a small island in the southern hemisphere. The player is not cast as a human teenager, but as a brand new robot created by Dr. Hopes from Volcano Town. This time, it is not possible to marry or form romantic relationships with villagers.
The gameplay has undergone significant changes compared to previous entries in the series. Many of these changes are improvements and fixes to exploits in earlier titles. One major improvement is the ability to walk through crops that have been planted. Seeds are now planted in individual 1x1 squares, rather than in 9x9 areas. Players can also purchase seeds individually, rather than in bags of nine. Crops and flowers are no longer destroyed if accidentally dropped on the ground for an extended period.
Crops grown in the wild have specific growth periods and schedules for harvesting, unlike previous games where they were available every day. The entire field is not available at the start of the game; instead, it needs to be unlocked by sealing it with gems obtained from story quests and cave exploration. Time has also been revised, allowing players to choose their wake-up time before 9 PM, but only if they go to bed before that time.