Mitsume ga Tooru

Mitsume ga Tooru (translates to The Three-Eyed One) is based on the manga and anime of the same name. You control Hosuke Sharaku - a boy with a third eye on his forehead and of terrifying power. This power is unleashed when his third eye is open so he is wearing a bandage to seal his power and remove any memories of his true nature. In the game, another three-eyed man with great powers appears and attacks a city. He also kidnaps Sharaku's friend Wato who watches unable to do anything. Sharaku then, with the bandage removed, begins his quest to save Wato from this man.