The game's Clash Mode returns, allowing players to unleash powerful tackles on opponents by hitting them with dirty and late hits. Injuries are still present, with enhanced graphics showing realistic damage to the players' bodies through x-rays. A new feature allows players to pinpoint the location of an opposing player they wish to hit, adjusting the size of the target area to affect the chances of a successful tackle.
Online capabilities enable players to connect and engage in quick versus matches against friends or participate in online campaign modes. The game also features downloadable content and voice acting from NFL legends, including Lawrence Taylor as Quentin Sands, alongside comedians Jay Mohr and Frank Caliendo.