In gameplay, Karaoke Revolution w/ Microphone focuses on karaoke-style performances, where players use a virtual microphone to sing along with backing tracks. The game features a wide range of songs from various genres, including pop, rock, and hip-hop. Players can choose to perform solo or compete against friends in local multiplayer mode.
The gameplay is designed to be accessible to players of all skill levels, with features such as auto-mode, which helps new singers get started. As players progress through the game, they unlock new songs and characters, adding to the overall replay value.