Mother Russia Bleeds

The game supports up to four local players working together, but with 'friendly fire'. The game can also be played in single-player, optionally with additional characters as bots controlled through the AI. The gameplay takes place in various locations such as prisons, ghettos, sex clubs and laboratories, with vivid depictions of gore and explicit violence. Characters visually sustain damage and brutal fatalities can be performed.

The controls include horizontal and vertical movement, jumping, and dashing. Basic attacks are a punch and a kick that can be combined into combos. It is also possible to grab and hit or throw characters, slide or punch while dashing, mash downed opponents, attack in the air, and charge punches. The game incorporates lots of weapons like bats and knives. Fighting 20 or 30 characters at once is not uncommon, as each character has different attacks, strengths and weaknesses.

A character's health bar is tied to the Nekro drug. Certain defeated opponents will convulse for a short time, providing a brief window to sample their body to extract the Nekro drug. This fills a syringe in the top left corner; however, a character is very vulnerable while doing so. The liquid can be injected to restore some life or go berserk. While berserk, movement becomes faster and attacks are much more powerful for a short while. Sampling Nekro is largely a risk-reward mechanic.

Next to the main story mode, there is a wave-based arena survival mode, supporting the same type of player options. Each character has different statistics based on force, jump, range and speed. Next to each character, an ability can be selected, but most of these need to be unlocked first.