River City Girls is a beat 'em up set in 1970s New York City. The game follows the story of two hard-boiled private investigators, Kyoko and Misako, who team up to take down a corrupt crime lord and his accomplices.
The duo must navigate through the city's streets, fighting against henchmen and bosses in a series of side-scrolling stages. Along the way, they can collect special moves and items that aid them in their quest for justice.