Cosmo Police Galivan II brings back the same challenge as its predecessor, but with a greater sense of urgency. The universe is once again threatened by alien invaders, and this time they're targeting Earth. Players must navigate through hordes of enemies with minimal items or leveling up to take them down.
The gameplay revolves around three playable characters, each with unique stats but similar movesets. Each character has a standard punch or kick, a sweeping kick, an uppercut, and a charged ranged attack. Players can earn stat points throughout the game and at level start and end to increase their character's HP, defense, jump height, and attack strength.
Cosmo Police Galivan II also features a two-player versus mode, where both players can choose from three main characters, with the second player able to select from one of four normal enemy types.