The story of Resident Evil: Umbrella Chronicles Shot Blaster is set during a fictional apocalypse where a sinister corporation called the Umbrella Corporation has unleashed a deadly virus that turns people into zombies. The player takes on the role of Chris Redfield and Leon S. Kennedy, two agents sent to investigate the outbreak and save humanity.
The gameplay in Resident Evil: Umbrella Chronicles Shot Blaster is action-packed and fast-paced, with an emphasis on shooting and exploration. Players control Chris Redfield and Leon S. Kennedy as they navigate through levels, fighting against hordes of zombies and other enemies. The game features a unique 'shot blaster' style gameplay mechanic, where players must fire their guns at specific targets to earn points and progress through the story.