Baseball Stars 2 is a follow-up to Baseball Stars Professional , featuring fast-paced arcade style baseball with six fictitious teams. Each team has its own strengths and weaknesses, adding variety to the gameplay. The game offers two difficulties: Beginner , where the ball is fielded automatically for the player, and Exciting , where the player must do it manually.
The gameplay is based on standard baseball rules, but with added power-ups that can be picked up during the game. These include enhancements to the pitcher's speed and the batter's hitting ability. The player can also substitute other players, but are limited to three substitutions per game. The game features 2D graphics and comic-style cutscenes to illustrate the action.