Second Sight is an action-adventure game that follows John Vattic's journey as he tries to uncover the truth about his past and his newfound psychic powers. After waking up in a high-security medical facility with no memory of how he got there, John begins to piece together fragments of his life through a series of flashbacks to his days working with WinterICE. His mission is to locate surviving members of the group, clear his name, and understand what happened to him.
The gameplay in Second Sight allows players to experience a mix of stealth, violence, and psychic powers. John can control the protagonist from a third-person perspective, switching to first-person view under specific circumstances. Players can use telekinesis, healing, charm, projection, possession, and two types of psychic attacks to overcome challenges, often opting for a combination of methods or relying on stealth tactics.