Dead Head Fred is an action game that tells a "classic tale of murder, corruption, revenge and... interchangeable heads". The main character is Fred Neuman. He's a private detective in the town of Hope Falls. During his investigations, he gets too involved with the dealings of the mob, so he's lured into a trap and beheaded. Shortly after his murder, he's found by Dr. Friedrich Steiner, who resurrects his body, and places his brain and eyes into a jar. From here begins the journey of Fred for revenge.
Gameplay revolves around controlling Fred as he navigates through levels, fighting enemies and using his special powers to overcome obstacles. The heads system allows players to switch between different heads, each with its unique abilities, to tackle challenges in various ways.
Dead Head Fred was released on the PlayStation Portable (PSP) on 26 October 2007, and is classified as an Action & Adventure game.