Players take control of Ratchet, who is armed with a range of new and familiar guns, including the Agents of Doom and Hypershot. As he navigates through levels, he can collect upgrades for his arsenal and buy new mods using an RPG-like experience system, similar to Up Your Arsenal. Additionally, players can gather pieces of armor sets, which can be worn and combined to give Ratchet extra abilities.
Gameplay is complemented by various minigames, including hovercraft races, space battles, and battle robot arenas. These add a fun twist to the platforming elements, keeping players engaged throughout their journey. Multiplayer options are also available, allowing friends to compete in deathmatch, team deathmatch, capture the flag, or the Iron Lombox Challenge.