War of the Monsters is a sci-fi melee fighting game where an alien race attacks Earth, but humans find a way to create monsters using strange liquid from damaged UFOs. These creatures wreak havoc on the planet, forcing players to fight them to save Earth.
The gameplay involves single or two-player battling in various modes, including "Adventure", "Free For all", "Endurance", "Elimination", and Mini-Games. Players can collect health, weapon, energy, and special pick-ups during battles to aid their progress. The game also features saving options after each level, allowing players to load their saved progress later. Tokens earned in adventure mode battles can be used to purchase new monster costumes, arenas, and mini-games.