The gameplay is fast-paced and action-packed, with a focus on hack-and-slash combat. Players control either Blanc or Neptune as they navigate through levels, fighting off waves of zombies and bosses. The game features a variety of attacks and combos that can be chained together for high damage output. With a unique art style and quirky humor, MegaTagmension Blanc + Neptune vs. Zombies is a fun and challenging Beat'em Up experience.