Nicktoons: Attack of the Toybots is a side-scrolling platform game featuring popular Nicktoons characters such as Spongebob Squarepants, Timmy Turner, Jimmy Neutron, Gir, Ren, and Tak. Professor Calamitous fuels his army by feeding fairies krabby patties, which allows them to emit a gas that can fuel robots.
Players control their chosen character as they navigate through the Professor's toy factory, fighting evil robot copies of themselves. The main gameplay element is platforming, with actions such as jumping across gaps and collecting blue energy cubes to unlock more playable characters. Bonus levels allow players to take control of a Mech suit used to destroy the factory.
The game features multiple universes based on the franchises of its characters, each with their own set of playable characters for each level and universe.