Gameplay revolves around combat and exploration. Players control Spider-Man as they swing through Manhattan, battling enemies and solving puzzles to progress. The combat system allows for a mix of melee and web-slinging attacks, while exploration involves using Parker's detective skills to gather information and uncover hidden paths.
The game features a variety of abilities, including web-shooters, that can be upgraded throughout the game. As players defeat enemies and complete objectives, they earn experience points to upgrade these abilities, giving Spider-Man more options in combat.