Testament of Sherlock Holmes is an action & adventure game for Xbox 360 set in London, 1898. The game follows an original story about Sherlock Holmes and his partner Watson as they investigate a series of mysterious events. After solving a case involving stolen jewels, the necklace turns out to be fake, and Holmes becomes incriminated. The player then takes on the role of Watson, who must investigate whether Holmes is truly implicated.
The gameplay focuses on investigations, with an open-world environment that allows players to explore different locations and follow leads or ignore them. Characters can run to travel faster, and items in the environment are highlighted with a magnifying glass. Players can inspect these items up close to gather clues or perform actions like moving an item. The game also features puzzles that require deductive reasoning, where the player's answers affect how the evidence is used afterwards.
The game offers various ways to progress, including conversations with suspects, where different approaches can be used to catch them off-guard. Other elements of the menu provide context, a summary of dialogues, decorations, and honors, as well as a map of London. The game also includes a "sixth sense" system that provides hints when needed, which can be activated based on the chosen difficulty level.