Pipe Dreams 3D is set on the planet Pipe, a peaceful place that's turned into a disaster when one evil Pipe decides she doesn't like the other Pipes or their ways. She unleashes foul-smelling, toxic Green Flooze from her flying saucer, covering the entire planet and its inhabitants in the noxious substance.
Players take on the role of a brave Pipe who must challenge the evil Pipe Queen to clear the planet of the Green Flooze and defeat her. The game involves using different shaped pieces of pipe to form longer pipes that control the flow of the Flooze around the screen, with the ultimate goal of reaching a plug hole.
The gameplay is centered around puzzle-solving, as players must navigate through 18 continents, each with its own unique characters and hazards. There are also power-ups to collect, including jewels and coins, which can be used to aid in the player's progress.