Dr. Mario / Puzzle League box art for GameBoy Advance
Dr. Mario / Puzzle League screenshot 2 for GameBoy Advance
Dr. Mario / Puzzle League screenshot 3 for GameBoy Advance
Dr. Mario / Puzzle League screenshot 4 for GameBoy Advance
GameBoy Advance system logo
Complete
$33.89
Loose $21.23
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Dr. Mario / Puzzle League

Dr. Mario / Puzzle League

↘ 3.3%
(GameBoy Advance - US, Puzzle)
🇺🇸
US
🇪🇺
PAL
Released On:
28 Nov 2005
Dr. Mario & Puzzle League is a dual-game cartridge for the GameBoy Advance console. The game's story revolves around Dr. Mario as he battles viruses to save the world.
The gameplay of Dr. Mario & Puzzle League involves various modes, including Classic, Flash, versus CPU, and Vertical in Dr. Mario, and Marathon, versus CPU, Timed, Line, Garbage, and Puzzle in Puzzle League. In Dr. Mario, players must arrange pills to wipe out viruses, while in Puzzle League, players rearrange colored tiles to eliminate groups of like types.
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US Regional Pricing
Prices as of 09 Oct 2026
Typical $34.99–$35.00 (last 90 days)
2022202320242025202601020304050Complete: $33.89Loose: $21.23
New
Complete
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Manual
Smoothed
Log · Auto
Medians
Market activity: active · about 65 sales a year
Activity is a 12-month sales count. Dashed segments rest on two sales a year or fewer.

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