Cloudy with a Chance of Meatballs is based on the 2009 computer-animated film of the same name. The player takes on the role of Flint Lockwood, an inventor trying to solve the hunger problem in his town by creating a machine that turns water into food. However, things take a turn for the worse when the machine gets out of control and starts raining food on Flint's town. Now, it's up to him to stop the machine and get rid of the abundance of food.
The gameplay involves fighting and solving puzzles through twenty levels, using Flint's self-created gadgets such as a heat gun made from a hair dryer or a mechanical boxing glove. Each level features thirty specific food items that must be destroyed to unlock a piece of a blueprint for a special item.
The game also features a co-op mode, where a second player can join in anytime as Flint's pet monkey Steve.