Harry Potter and the Half-Blood Prince follows the story of Harry Potter as he faces off against Lord Voldemort and his followers. As Harry navigates the challenges of Hogwarts, he must also uncover the secrets of an old potions textbook known as the Half-Blood Prince's notes.
The gameplay is a mix of action, adventure, and puzzle-solving. Players can explore the school at their own pace between chapters, but they can also use special items such as portraits to teleport or summon ghosts for assistance. The main objective is to find 150 hidden crests, which grant achievements and trophies.
The game features three mini-games: magic duels, brewing potions, and quidditch. In magic duels, players must recreate spell movements using their input device to defeat opponents. Quidditch is a reaction test where the player controls Harry's broom as it flies through rings or avoids obstacles.
Brewing potions requires players to recreate recipes using ingredients in the correct order before time runs out. Making mistakes results in smoke, costing valuable time. With these challenges and others, players must master the magical world of Hogwarts.