Destroy All Humans 2 box art for Xbox
Destroy All Humans 2 screenshot 3 for Xbox
Destroy All Humans 2 title screen for Xbox
Destroy All Humans 2 media 5 for Xbox
Destroy All Humans 2 logo for Xbox
Xbox system logo
Complete
$11.55
Loose $8.47
Manage Collection
Home
›
Xbox
›
Destroy All Humans 2

Destroy All Humans 2

↗ 22%
(Xbox - US, Third Person Shooter)
🇺🇸
US
🇪🇺
PAL
Xbox logo
Developed_By:
Electronic Arts
Published_By:
THQ
Released On:
26 Oct 2006
Also available on:
Playstation 2
Destroy All Humans 2 is a third-person shooter game set in an alternate universe where aliens have invaded Earth. Players take on the role of Cryptosporidium-137, a psychopathic alien who must use his mind control powers to terrorize humanity and destroy all humanoids on the planet.
The gameplay involves using Cryptosporidium's powers to infiltrate human cities, recruit humans as mindless drones, and then send them to do his bidding. The game features a variety of missions, including destroying military bases, hijacking aircraft, and stealing valuable technology. With a mix of action, strategy, and dark humor, Destroy All Humans 2 offers a unique gaming experience.
Destroy All Humans 2 was released on the Xbox console on October 17, 2006.
YouTube
Reddit
Twitch
Wikipedia
DB
IGDB
RG
RAWG
M
Metacritic
󱑆
HowLong
GF
GameFAQs
Xbox Platform Trends
US Regional Pricing
Prices as of 30 Jul 2026
Typical $10.55–$11.55 (last 90 days)
2022202320242025202602468101214Complete: $11.55Loose: $8.47
New
Complete
Loose
Box
Manual
Smoothed
Log · Auto
Medians
Market activity: active · about 164 sales a year
Activity is a 12-month sales count. Dashed segments rest on two sales a year or fewer.

Related Games

Common
🙂 7.2/10
Destroy All Humans Xbox US box art
Xbox logo
Destroy All Humans
$10.96 (Complete)
Jun 2005
Scarce
🙂 7.2/10
Destroy All Humans PAL Playstation 4 PAL box art
PAL Playstation 4 logo
Destroy All Humans
$9.36 (Complete)
Jul 2020

More Xbox Third Person Shooter

Abundant
😊 7.9/10
Halo: Combat Evolved Xbox US box art
Xbox logo
Halo: Combat Evolved
$15.24 (Complete)
Nov 2001
Abundant
😊 8.2/10
Halo 2 Xbox US box art
Xbox logo
Halo 2
$13.22 (Complete)
Nov 2004
Abundant
Conker Live and Reloaded Xbox US box art
Xbox logo
Conker Live and Reloaded
$61.57 (Complete)
Jun 2005
Very Common
Star Wars Battlefront Xbox US box art
Xbox logo
Star Wars Battlefront
$13.73 (Complete)
Sep 2004
Very Common
😍 8.7/10
Half-Life 2 Xbox US box art
Xbox logo
Half-Life 2
$16.99 (Complete)
Nov 2005
Very Common
😊 8.3/10
Max Payne Xbox US box art
Xbox logo
Max Payne
$15.47 (Complete)
Dec 2001
Very Common
Max Payne 2 Fall of Max Payne Xbox US box art
Xbox logo
Max Payne 2 Fall of Max Payne
$14.01 (Complete)
Nov 2003
Very Common
Halo 2 Multiplayer Map Pack Xbox US box art
Xbox logo
Halo 2 Multiplayer Map Pack
$14.83 (Complete)
Jul 2005
Very Common
🙂 7.0/10
Red Dead Revolver Xbox US box art
Xbox logo
Red Dead Revolver
$20.00 (Complete)
May 2004
Very Common
😊 8.4/10
Chronicles of Riddick: Escape from Butcher Bay Xbox US box art
Xbox logo
Chronicles of Riddick: Escape from Butcher Bay
$16.71 (Complete)
Jun 2004
Search Games
Popular Consoles
1980s
ZX Spectrum
1982 • 4774 games
Commodore 64
1982 • 1694 games
1990s
Playstation
1994 • 2231 games
Super Nintendo
1990 • 1226 games
2000s
Xbox 360
2005 • 3116 games
Playstation 2
2000 • 3088 games
2010s
Nintendo Switch
2017 • 5181 games
Playstation 4
2013 • 5181 games
2020s
Playstation 5
2020 • 2764 games
Xbox Series X
2020 • 1302 games
Trending Now
Tony Hawk’s Pro Skater 4
Xbox
The Sims 2
Xbox
MX Superfly
Xbox
Time Splitters Future Perfect
Xbox
Phantasy Star
Sega Master System
By Year
1978
1979
1980
1981
1982
1983
1984
1985
1986
1987
1988
1989
1990
1991
1992
1993
1994
1995
1996
1997
1998
1999
2000
2001
2002
2003
2004
2005
2006
2007
2008
2009
2010
2011
2012
2013
2014
2015
2016
2017
2018
2019
2020
2021
2022
2023
2024
2025
2026
About
About Us
Contact
Privacy Policy
Terms of Service
Imprint
Copyright / DMCA
Popular Games
Sonic CD
Jungle Strike
Gremlins
Connect With Us
© 2026 RetroGold. All rights reserved.
Home
Games
Deals
Trade
Trends
Game Detection
Contribute
Lexicon