Growlanser: Heritage of War takes place on an isolated island continent where a powerful weapon called the "Admonisher" brought an end to 20 years of war. However, after the old men of the "Peace Maintenance Brigade" can no longer maintain peace, another outbreak occurs among the continent's inhabitants.
The continent is plagued by a mysterious famine, leaving citizens fighting over remaining fertile land as cities are attacked by fierce amphibious monsters called "Screapers".
The gameplay in Growlanser: Heritage of War involves real-time battles where players must develop strategies and tactics quickly due to the lack of a traditional battle map.