Gameplay features a mix of single-player and multiplayer modes, including a cooperative Zombies mode that returns from previous games. Players can also participate in large-scale game modes such as Arms Race, where two teams of twelve players compete to capture five bases.
Vanguard is integrated with Call of Duty: Warzone , allowing players to progress and use weapons, operators, and other cosmetics items across both titles. This cross-game functionality provides a seamless experience for players who engage with multiple titles in the series.