Wall-E is based on the 2008 Disney/Pixar movie of the same name. The cutscenes closely follow the movie, with added scenes and dialogue to give more to the game. The gameplay is a basic platformer with some strategy involved, using Wall-E to navigate areas and pick things up to use. Players must also figure out ways to reach far-out areas due to Wall-E's limited jump capacity. There are also racing stages designed for the robot, EVE, where the player flies through constricted areas, avoiding obstacles.
This version of the game differs from others and has nine explorable worlds. The Wii version features three head-to-head multiplayer modes.