Resident Evil: Operation Raccoon City

The game is not part of the series' canon and details a hypothetical scenario set in September 1998 around the same time as Resident Evil 2 and Resident Evil 3: Nemesis. Players control a member of USS, the Delta security team of the Umbrella Corporation nicknamed Wolfpack. Their initial mission is to team up with HUNK, the Alpha Leader to assist with the infiltration and secure the virus.

At the start of each mission the player assembles a team of four characters based on a pool of six with different classes. There is Vector (Recon), Bertha (Medic), Four Eyes (Field Scientist), Beltway (Demolition), Lupo (Assault), and Spectre (Surveillance). Each character has a primary and secondary weapon, as well as passive and active abilities tied to their class. The game is played from a third-person perspective and combines shooting with cover mechanics.

Opponents include infected humans as the T-virus has leaked city-wide as well as mercenaries part of the Umbrella's Biohazard Countermeasure Service (UBCS) who protect Birkin and turn out not to be reliable partners. The player controls a single character as the other team members are controlled by the AI. It is not possible to switch between team members but the game can be played cooperatively with four human players, each controlling a team member.

Next to the shooting, the use of abilities, and various melee attacks, there are two additional mechanics that are used. The first is the use of bioweapons that causes members of the same team or infected to fight each other. Secondly, when the player's character is bitten, he risks getting infected. Health is drained and the character is eventually turned, attacking the team members (while the player is not in control) until an immunisation spray cancels it out.

Multiplayer adds a second team of six characters from the United States Special Ops (USSO) with similar abilities: Willow, Dee-Ay, Tweed, Harley, Shona and Party Girl. The Heroes Mode pits famous characters from the series' franchise against each other. The game modes include Team Attack (team deathmatch), Biozahard (capture the flag), Survivors (survive with a team until the helicopter arrives).