Arthur and the Invisibles: The Game is an action-adventure based on the mostly animated film from director Luc Besson, who also wrote the children's books it originated from. It follows the film's storyline after the live-action part where a boy must save his grandmother's house from a greedy developer by finding a treasure that his grandfather went missing in searching for it in the magical land of the tiny Minimoy. When the boy Arthur enters a portal to their land, he shrinks in size and changes his appearance so he becomes like a Minimoy also. Arthur and his two friends, princess Selenia and her brother Bétamèche, try to save the Minimoys from certain destruction.
The gameplay starts with a tutorial that teaches you movement and combat, as well as how to move objects and flip switches. The action begins when a Minimoy ceremony is interrupted by enemy mosquitoes. You have to alternately play as all three characters and use their special abilities to fight, solve puzzles, fly, and drive. Arthur can smash spiderwebs and climb, while Selenia can cut through foliage, and Bétamèche can crawl through small spaces and packs an upgradable projectile-based weapon. Defeating enemies that have special keys is necessary to open gates and progress in the game. There are also racing sections, and scenes from the film move the story along from one set piece to another.