The object of King of the Monsters 2 is similar to its predecessor. Choose from three monsters: a large lizard, a large robotic ape, and a huge mutant human. Then walk through each city, making sure to destroy everything in sight, including planes, buildings, and other creatures. When smashed, some buildings reveal power-ups that make your character more powerful. At the end of each city, you go head-to-head with the boss creature.
The gameplay is fast-paced and action-packed, with short stages and frequent battles against smaller monsters. You also have to navigate through cities without getting hit by enemy attacks or falling off cliffs. The game features a variety of power-ups that can be collected during the levels, giving you an edge over your opponents.